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  • Lab Scale M-110P
    “Plug and Play” Biopharma Lab Scale Homogenizer

    M-110P Microfluidizer® processor for Continuous High Shear cGMP-Ready Fluid Processing

    This new lab-scale model was developed to meet the needs for cGMP processing of small batch sizes. Utilizing Microfluidizer® fixed-geometry interaction chamber technology and a ceramic plunger, the M-110P processes a wide variety of fluids, including oil-in-water emulsions, solids-in-liquid suspensions, and cell disruption of bacteria and the most difficult cells, like yeast — in as few as one or two passes. What’s more, the process is repeatable and guaranteed to scale up to pilot and/or production volumes.

  • Lab Scale Microfluidizer Processor M-110P

How It Works

The M-110P models contain an on-board 1.5 kW (2 HP) electric/hydraulic drive that powers a single-acting intensifier pump. By adjusting process pressures from 138 – 2068 bar (2,000 – 30,000 psi), the process can be optimized to achieve the desired results.

The intensifier pump drives the product at constant pressure through the interaction chamber. The product stream accelerates to high velocities as it goes through the fixed-geometry microchannels, creating high shear and impact forces that produce the appropriate results.

After leaving the interaction chamber, the product flows through the external cooling coil. Once the desired temperature is achieved, the product may be recirculated for further processing or advanced to the next step in the process.

Recommended Uses

The M-110P benchtop homogenizer model is recommended for:  

  • Stable Nanodispersions
  • Stable Nanoemulsions
  • Cell Rupture/ Cell Disruption (yeast, E. coli, etc.)
  • Microencapsulation in Polymers, Liposomes and Oils
  • Deagglomeration

Unique Benefits

The “Plug and Play” M-110P laboratory Microfluidizer®:

  • Requires a minimum sample size of 36 ml
  • Achieves processing pressures up to 2068 bar (30,000 psi)
  • Produces product flow rate up to 120 ml/min (100 ml/min on 50 Hz model)
  • Meets ASME-BPE compliance standard
  • Is cGMP ready
  • Features tube-in-tube pharma-grade heat exchanger
  • Contains inlet and outlet thermocouples with display on touch screen
  • Includes pressure transducer with display on touch screen
  • Provides a 7" HMI color touch screen control
  • Offers the highest shear rate
  • Guarantees scalability
  • Meets CE marking requirements
  • Offers customizable options to suit every application

Standard Features

  • 300 ml glass feed reservoir
  • Diamond interaction chamber
  • Ceramic (Zirconia) plunger
  • Stainless steel enclosure
  • Electric/hydraulic drive method
  • Standard one-year warranty

Optional Features

  • 400 ml stainless steel open reservoir
  • 1 liter stainless steel open reservoir
  • 2 liter stainless steel open reservoir
  • 2 liter pressurized stainless steel reservoir
  • 7.6 liter pressurized stainless steel feed tank
  • Manual priming and purging cylinder
  • Seal quench system
  • Additional interaction chamber
  • Additional auxiliary processing module (ceramic)
  • IQ/OQ on-site execution
  • FAT, SAT, on-site startup and operator training
  • Preventive maintenance service
  • Extended warranty

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Proven Results

Let us demonstrate how a Microfluidizer® can achieve your nanomaterial processing and product quality goals.

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